You can happily stack five hands with this build. In order to do so you will need to make sure that you have both Regeneration and Protection.
To deal with the one-shot mechanic from , you will need to use your F3 skill - . This will provide you with a four second Invulnerability frame. will be up for every .
is your fallback and will let you survive even if you forget to use . This trait, in the Soulbeast Trait Line, will cause you to instead of getting Downed . This trait has a 60 second Cooldown and so will not be up for every but it is a nice backup if you mess up.